Hi Lindsay,
The problem seems to be the '+' character in this folder name: "Quality Control + System Suitability". This folder was created in 2021 and hasn't been renamed since. So it is odd that the uploads just started failing. The last successful upload in a subfolder was in 11/2022, and that was with Skyline-daily (64-bit) 21.2.1.403 (b37df497b). Which version of Skyline are you using now? I will try to track down what changed since Skyline-daily 21.2.1.403 that is causing the '+' character to not be encoded correctly in the URLs being sent by Skyline to Panorama.
The workaround for now would be to replace the '+' in the folder name with something else, e.g. rename the folder to "Quality Control & System Suitability". Is that acceptable?
Thanks for reporting the bug!
-Vagisha